Design, synthesis and biological evaluation of novel 2,4-diaminopyrimidine cinnamyl derivatives as inhibitors of FAK with potent anti-gastric cancer activities-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of novel 2,4-diaminopyrimidine cinnamyl derivatives as inhibitors of FAK with potent anti-gastric cancer activities

Published:2023-12 Issue: Volume:141 Page:106895
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Liu Yang,Kong Li-Jun,Li Na,Liu Yun-He,Jia Mei-Qi,Liu Qiu-Ge,Zhang Sai-Yang,Song Jian

Funder

National Natural Science Foundation of China

Science and Technology Department of Henan Province

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference34 articles.

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3. The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review;Zhou;J. Exp. Clin. Cancer Res.,2019

4. FAK in Cancer: From Mechanisms to Therapeutic Strategies;Chuang;Int. J. Mol. Sci.,2022

5. FAK and paxillin, two potential targets in pancreatic cancer;Kanteti;Oncotarget,2016

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3. Annual review of PROTAC degraders as anticancer agents in 2022;European Journal of Medicinal Chemistry;2024-03

4. Roles and inhibitors of FAK in cancer: current advances and future directions;Frontiers in Pharmacology;2024-02-12