Design, synthesis and bioactivity evaluation of self-assembled PROTACs based on multi-target kinase inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis and bioactivity evaluation of self-assembled PROTACs based on multi-target kinase inhibitors

Published:2023-05 Issue: Volume:134 Page:106439
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Si Ru,Zhu Huanjie,Wang Jin,Zhang Qingqing,Li Yanchen,Pan Xiaoyan,Zhang Jie

Funder

Science Fund for Distinguished Young Scholars of Tianjin

National Natural Science Foundation of China

Key Research and Development Projects of Shaanxi Province

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference17 articles.

1. Proteolysis-targeting chimeras in drug development: a safety perspective;Moreau;Br. J. Pharmacol.,2020

2. Proteolysis-targeting chimeras (PROTACs) in cancer therapy;Li;Mol. Cancer,2022

3. PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics;Khan;Oncogene,2020

4. Advancing targeted protein degradation for cancer therapy;Dale;Nat. Rev. Cancer,2021

5. How big is too big for cell permeability;Matsson;J. Med. Chem.,2017

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1. Click Chemistry and Targeted Degradation: A Winning Combination for Medicinal Chemists?;ChemMedChem;2023-09-14

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