Synthesis of and anti-fibrotic effect of pyrazole derivative J-1048: Inhibition of ALK5 as a novel approach to liver fibrosis targeting inflammation-Reference-Cited by-同舟云学术

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Synthesis of and anti-fibrotic effect of pyrazole derivative J-1048: Inhibition of ALK5 as a novel approach to liver fibrosis targeting inflammation

Published:2023-10 Issue: Volume:139 Page:106723
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Yang Hong-Xu,Guo Fang-Yan,Lin Yong-Ce,Wu Yan-Ling,Nan Ji-Xing,Jin Cheng-Hua,Lian Li-Hua

Funder

Natural Science Foundation of Jilin Province

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference48 articles.

1. Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues;Parola;Mol. Aspects Med.,2019

2. Liver fibrosis. Foreword;Schwabe;Semin. Liver Dis.,2015

3. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010;Lozano;Lancet,2012

4. Liver diseases: A major, neglected global public health problem requiring urgent actions and large-scale screening;Marcellin;Liver Int.,2018

5. Hepatic fibrosis;Kershenobich;Rev. Gastroenterol. Mex.,2012

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2. Synthesis and biological evaluation of panaxadiol ester derivatives possessing pyrazole and pyrrole moiety as HIF-1α inibitors;Fitoterapia;2024-09

3. Synthesis and biological evaluation of sulfonamide derivatives containing imidazole moiety as ALK5 inhibitors;Molecular Diversity;2024-08-30

4. Synthesis of amide derivatives containing the imidazole moiety and evaluation of their anti‐cardiac fibrosis activity;Archiv der Pharmazie;2024-04-28

5. Synthesis and anti-liver fibrosis activity of imidazole and thiazole compounds containing amino acids;European Journal of Medicinal Chemistry;2024-04

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