Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity relationship-Reference-Cited by-同舟云学术

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Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity relationship

Published:2023-12 Issue: Volume:141 Page:106893
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Thakur Amandeep,Rana Mandeep,Ritika ,Mathew Jacob,Nepali Sanya,Pan Chun-Hsu,Liou Jing Ping,Nepali Kunal

Funder

National Science and Technology Council

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference195 articles.

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2. Targeting DNA repair in cancer: current state and novel approaches;Klinakis;Cell. Mol. Life Sci.,2020

3. Mammalian single-strand break repair: mechanisms and links with chromatin;Caldecott;DNA Repair,2007

4. Mechanisms of DNA damage, repair, and mutagenesis;Chatterjee;Environ. Mol. Mutagen.,2017

5. PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes;Gupte;Genes Dev.,2017

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1. Poly (ADP-ribose) polymerase (PARP) inhibitors as anticancer agents: An outlook on clinical progress, synthetic strategies, biological activity, and structure-activity relationship;European Journal of Medicinal Chemistry;2024-08

2. Design, synthesis, and evaluation of novel stilbene derivatives that degrade acidic nucleoplasmic DNA-binding protein 1 (And1) and synergize with PARP1 inhibitor in NSCLC cells;Journal of Enzyme Inhibition and Medicinal Chemistry;2024-07-29

3. Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation;European Journal of Medicinal Chemistry;2024-07

4. Innovations in Precision Oncology: Biomarker-Driven Approaches for Enhanced Cancer Therapy;ACS Medicinal Chemistry Letters;2024-01-25

5. Novel PARP7 Inhibitors for Treating Cancer;ACS Medicinal Chemistry Letters;2023-11-04

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