Pyrimidine-morpholine hybrids as potent druggable therapeutics for Alzheimer’s disease: Synthesis, biochemical and in silico analyses-Reference-Cited by-同舟云学术

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Pyrimidine-morpholine hybrids as potent druggable therapeutics for Alzheimer’s disease: Synthesis, biochemical and in silico analyses

Published:2023-12 Issue: Volume:141 Page:106868
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Zaib Sumera,Younas Muhammad Tayyab,Khan Imtiaz,Ali Hafiz Saqib,McAdam Christopher John,White Jonathan M.,Jaber Fadi,Awwad Nasser S.,Ibrahium Hala A.

Funder

Deanship of Scientific Research, King Khalid University

King Khalid University

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference81 articles.

1. Novel small molecule therapeutic agents for Alzheimer disease: Focusing on BACE1 and multi-target directed ligands;Iraji;Bioorg. Chem.,2020

2. Current concepts in Alzheimer’s disease: a multidisciplinary review;Minati;Am. J. Alzheimers Dis. Other Demen.,2009

3. Alzheimer’s disease hypothesis and related therapies;Du;Transl. Neurodegener.,2018

4. Linarin, a glycosylated flavonoid, with potential therapeutic attributes: A comprehensive review;Mottaghipisheh;Pharmaceuticals.,2021

5. Cholinesterases: Roles in the brain during health and disease;Ballard;Curr. Alzheimer Res.,2005

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1. Design and discovery of anthranilamide derivatives as a potential treatment for neurodegenerative disorders via targeting cholinesterases and monoamine oxidases;International Journal of Biological Macromolecules;2024-06

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