Design, synthesis, and biological evaluation of pyrido[3,2-d]pyrimidine derivatives as novel ATR inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis, and biological evaluation of pyrido[3,2-d]pyrimidine derivatives as novel ATR inhibitors

Published:2023-07 Issue: Volume:136 Page:106535
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Duan Yunxin,Zhuang Lili,Xu Yerong,Cheng Haodong,Xia Jiawei,Lu Tao,Chen Yadong^ORCID

Funder

China Pharmaceutical University

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference48 articles.

1. Targeting the DNA damage response in cancer;O’Connor;Mol. Cell,2015

2. DDR-mediated crosstalk between DNA-damaged cells and their microenvironment;Malaquin;Front. Genet.,2015

3. The DNA-damage response in human biology and disease;Jackson;Nature,2009

4. Directing the use of DDR kinase inhibitors in cancer treatment;Brandsma;Expert Opin. Invest. Drugs,2017

5. Targeting ATR in cancer;Emilio;Nat. Rev. Cancer,2018

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies;Journal of Medicinal Chemistry;2024-07-25

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