Precise prediction of activators for the human constitutive androstane receptor using structure-based three-dimensional quantitative structure–activity relationship methods
Author:
Publisher
Elsevier BV
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology
Reference38 articles.
1. An update on the constitutive androstane receptor (CAR);Molnár;Drug Metab Drug Interact,2013
2. Small-molecule modulators of the constitutive androstane receptor;Cherian;Expert Opin Drug Metab Toxicol,2015
3. The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene;Honkakoski;Mol Cell Biol,1998
4. The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene;Sueyoshi;J Biol Chem,1999
5. The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR;Sugatani;Hepatology,2001
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Computational Approaches in Preclinical Studies on Drug Discovery and Development;Frontiers in Chemistry;2020-09-11
2. The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds;International Journal of Molecular Sciences;2020-05-14
3. QSAR modeling of different minimum potency levels for in vitro human CAR activation and inhibition and screening of 80,086 REACH and 54,971 U.S. substances;Computational Toxicology;2020-05
4. Computational prediction of cytochrome P450 inhibition and induction;Drug Metabolism and Pharmacokinetics;2020-02
5. Prediction Model with High-Performance Constitutive Androstane Receptor (CAR) Using DeepSnap-Deep Learning Approach from the Tox21 10K Compound Library;International Journal of Molecular Sciences;2019-09-30
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3