Underlying mechanism of drug–drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8
Author:
Publisher
Elsevier BV
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology
Reference47 articles.
1. 57 varieties: the human cytochromes P450;Lewis;Pharmacogenomics,2004
2. UGT genomic diversity: beyond gene duplication;Guillemette;Drug Metab Rev,2010
3. Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily;Mackenzie;Pharmacogenet Genomics,2005
4. UGT3A: novel UDP-glycosyltransferases of the UGT superfamily;Meech;Drug Metab Rev,2010
5. Human UDP-glucuronosyltransferases: metabolism, expression and disease;Tukey;Annu Rev Pharmacol Toxicol,2000
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