CNS penetration of methotrexate and its metabolite 7-hydroxymethotrexate in mice bearing orthotopic Group 3 medulloblastoma tumors and model-based simulations for children-Reference-Cited by-同舟云学术

CNS penetration of methotrexate and its metabolite 7-hydroxymethotrexate in mice bearing orthotopic Group 3 medulloblastoma tumors and model-based simulations for children

Published:2023-02 Issue: Volume:48 Page:100471
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Perkins Rachel S.^ORCID,Davis Abigail,Campagne Olivia,Owens Thandranese S.^ORCID,Stewart Clinton F.^ORCID

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology

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3. WHO 2021 and beyond;Cotter;Pediatr Dev Pathol,2022

4. High-dose chemotherapy in children with newly diagnosed medulloblastoma;Lafay-Cousin;Cancers,2022

5. Variation of hepatic methotrexate 7-hydroxylase activity in animals and humans;Kitamura;IUBMB Life,1999

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