Development of covalent NLRP3 inflammasome inhibitors: Chemistry and biological activity
Author:
Funder
University of Turin
Publisher
Elsevier BV
Subject
Molecular Biology,Biochemistry,Biophysics
Reference175 articles.
1. Inflammasomes: mechanism of action, role in disease, and therapeutics;Guo;Nat. Med.,2015
2. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases;Dinarello;Nat. Rev. Drug Discov.,2012
3. Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion;He;Cell Res.,2015
4. What do we know about the inflammasome in humans?;Amin;Brain Pathol.,2017
5. Gain of function mutation and inflammasome driven diseases in human and mouse models;Cordero;J. Autoimmun.,2018
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