Unravelling the antifungal mode of action of curcumin by potential inhibition of CYP51B: A computational study validated in vitro on mucormycosis agent, Rhizopus oryzae

Author:

Prajapati JigneshORCID,Rao PriyashiORCID,Poojara LipiORCID,Goswami DweipayanORCID,Acharya DhavalORCID,Patel Saumya K.ORCID,Rawal Rakesh M.ORCID

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference62 articles.

1. Bioactivity of curcumin on the cytochrome P450 enzymes of the steroidogenic pathway;Castaño;Int. J. Mol. Sci.,2019

2. Oral intake of curcumin markedly activated CYP 3A4: in vivo and ex vivo studies;Hsieh;Sci. Rep.,2014

3. Curcumin as a promising antifungal of clinical interest;Martins;J. Antimicrob. Chemother.,2009

4. Quinoline based monocarbonyl curcumin analogs as potential antifungal and antioxidant agents: synthesis, bioevaluation and molecular docking study;Nagargoje;Chem. Biodivers.,2020

5. Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs;Jeffreys;Sci. Rep.,2019

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