The crystal structure of the S154Y mutant carbonyl reductase from Leifsonia xyli explains enhanced activity for 3,5-bis(trifluoromethyl)acetophenone reduction-Reference-Cited by-同舟云学术

The crystal structure of the S154Y mutant carbonyl reductase from Leifsonia xyli explains enhanced activity for 3,5-bis(trifluoromethyl)acetophenone reduction

Published:2022-05 Issue: Volume:720 Page:109158
ISSN:0003-9861
Container-title:Archives of Biochemistry and Biophysics
language:en
Short-container-title:Archives of Biochemistry and Biophysics

Author:

Li Jun,Dinh Tung^ORCID,Phillips Robert^ORCID

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference42 articles.

1. Efficacy and safety of aprepitant in the prevention of chemotherapy-induced nausea and vomiting: a pooled analysis;Jin;Support. Care Cancer,2012

2. Using aprepitant as secondary antiemetic prophylaxis for cancer patients with cisplatin-induced emesis;Wu;Support. Care Cancer,2012

3. Population pharmacokinetics of aprepitant and dexamethasone in the prevention of chemotherapy-induced nausea and vomiting;Nakade;Cancer Chemother. Pharmacol.,2008

4. Synthesis of the major isomers of aprepitant and fosaprepitant;Wan;Chin. Chem. Lett.,2013

5. Practical asymmetric synthesis of aprepitant, a potent human NK-1 receptor antagonist, via a stereoselective Lewis acid-catalyzed trans acetalization reaction;Zhao;J. Org. Chem.,2002

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structure-based reshaping of a new ketoreductase from Sphingobacterium siyangense SY1 toward α-haloacetophenones;International Journal of Biological Macromolecules;2024-10

2. Enzymatic synthesis of chiral alcohols using ketoreductases;Catalysis Reviews;2024-02-19

3. Microbial alcohol dehydrogenases: recent developments and applications in asymmetric synthesis;Organic & Biomolecular Chemistry;2024

4. A short‐chain carbonyl reductase mutant is an efficient catalyst in the production of (R)‐1,3‐butanediol;Microbial Biotechnology;2023-03-22

5. Structural analysis of an anthrol reductase inspires enantioselective synthesis of enantiopure hydroxycycloketones and β-halohydrins;Nature Communications;2023-01-21