Abstract
SummaryThe purpose of this review was to analyze the literature for potential next-day residual effects of zolpidem, a non-benzodiazepine hypnotic, following nighttime administration. Based on more than 30 international clinical trials involving more than 2,600 subjects/patients, it can be concluded that at the recommended doses of zolpidem 10 mg for adults and zolpidem 5 mg for the elderly, at single or repeated dosing, in healthy subjects or insomniac patients, zolpidem appears to induce minimal next-day residual effects. As for all sedative hypnotics, zolpidem is indicated for the short-term treatment of insomnia and is recommended to be taken only when the patient is able to get a full night's sleep before resuming usual activities.
Publisher
Cambridge University Press (CUP)
Subject
Psychiatry and Mental health
Reference90 articles.
1. The World Psychiatric Association. Task Force on sedative hypnotics
2. Transient insomnia associated with a three-hour phase advance of sleeptime and treatment with Zolpidem;Walsh;J Clin Psychopliarmacol,1990
3. The effects of Zolpidem on transient insomnia;Vogel;Sleep Res,1988
4. Influence of Zolpidem, fiunitrazepam and placebo on the cognitive and memory function in healthy subjects;Vaucher;Abstracts of the 18th Congress of the International Union of Therapeutics. Geneva, 22–24 Apr,1987
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