Mutation of autophagy-related gene ATG7 increases the risk of severe disease in patients with non-alcoholic fatty liver disease
Author:
Publisher
Elsevier BV
Subject
Gastroenterology,Hepatology
Reference9 articles.
1. Aberrant elevation of FTO levels promotes liver steatosis by decreasing the m6A methylation and increasing the stability of SREBF1 and ChREBP mRNAs;Tang;J Mol Cell Biol,2023
2. Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease;Moylan;Hepatology,2014
3. Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci;Stender;Nat Genet,2017
4. Rare ATG7 genetic variants predispose patients to severe fatty liver disease;Baselli;J Hepatol,2022
5. Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis;BasuRay;Proc Natl Acad Sci U S A,2019
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