Low-affinity conditions for agonists increase the binding of the antagonist []RX821002 to the α2B/C-adrenoceptor subtypes in human brain and rat kidney

Author:

Callado Luis F,Meana J.Javier

Publisher

Elsevier BV

Subject

Pharmacology

Reference17 articles.

1. Quantitative analysis of rat brain α2-receptors discriminated by [3H]clonidine and [3H]rauwolscine;Asakura;Eur. J. Pharmacol.,1985

2. Subtypes of α1- and α2-adrenergic receptors;Bylund;FASEB J.,1992

3. [3H]RX821002 (2-methoxyidazoxan) binds to α2-adrenoceptor subtypes and a non-adrenoceptor imidazoline binding site in rat kidney;Callado;Eur. J. Pharmacol.,1996

4. Does [3H]2-methoxy-idazoxan (RX821002) detect more alpha-2-adrenoceptor agonist high-affinity sites than [3H]rauwolscine? A comparison of nine tissues and cell lines;Erdbrügger;J. Pharmacol. Exp. Ther.,1995

5. New tools for human fat cell alpha-2A adrenoceptor characterization. Identification on membranes and on intact cells using the new antagonist [3H]RX821002;Galitzky;J. Pharmacol. Exp. Ther.,1990

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