Levosimendan increases L-type Ca2+ current via phosphodiesterase-3 inhibition in human cardiac myocytes

Author:

Ajiro Youichi,Hagiwara Nobuhisa,Katsube Yasuhiro,Sperelakis Nicholas,Kasanuki Hiroshi

Publisher

Elsevier BV

Subject

Pharmacology

Reference31 articles.

1. Phosphodiesterase inhibition in ventricular cardiomyocytes from guinea-pig hearts;Bethke;Br. J. Pharmacol.,1992

2. Mechanisms of the contractile effects of levosimendan in the mammalian heart;Boknı́k;J. Pharmacol. Exp. Ther.,1997

3. Inhibition of human cardiac cyclic AMP-phosphodiesterase by R80122, a new selective cyclic AMP-phosphodiesterase 3 inhibitor: a comparison with other cardiotonic compounds;Cheffoy;J. Pharmacol. Exp. Ther.,1992

4. Effects of levosimendan, a cardiotonic agent targeted to troponin C, on cardiac function and on phosphorylation and Ca2+ sensitivity of cardiac myofibrils and sarcoplasmic reticulum in guinea pig heart;Edes;Circ. Res.,1995

5. Two types of transient outward currents in adult human atrial cells;Escande;Am. J. Physiol.,1987

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