The relevance of supersaturation and solubilization in the gastrointestinal tract for oral bioavailability: An in vitro vs. in vivo approach

Author:

López Mármol Álvaro,Denninger Alexander,Touzet Antoine,Dauer Katharina,Becker Tim,Pöstges Florian,Pellequer Yann,Lamprecht Alf,Wagner Karl G.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference62 articles.

1. PH-metric logP 11. pKa determination of water-insoluble drugs in organic solvent–water mixtures;Avdeef;J. Pharm. Biomed. Anal.,1999

2. Equilibrium Solubility Measurement of Ionizable Drugs - Consensus Recommendations for Improving Data Quality;Avdeef;ADMET DMPK,2016

3. Development and validation of a stability-indicating HPLC method for analysis of celecoxib (CXB) in bulk drug and microemulsion formulations;Baboota;Acta Chromatogr.,2007

4. Accounting for the solubility–permeability interplay in oral formulation development for poor water solubility drugs: The effect of PEG-400 on carbamazepine absorption;Beig;Eur. J. Pharm. Biopharm.,2012

5. Excipient-Mediated Supersaturation Stabilization in Human Intestinal Fluids;Bevernage;Mol. Pharm.,2011

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