Zebularine suppressed gemcitabine-induced senescence and improved the cellular and plasma pharmacokinetics of gemcitabine, augmented by liposomal co-delivery-Reference-Cited by-同舟云学术

Zebularine suppressed gemcitabine-induced senescence and improved the cellular and plasma pharmacokinetics of gemcitabine, augmented by liposomal co-delivery

Published:2021-06 Issue: Volume:602 Page:120659
ISSN:0378-5173
Container-title:International Journal of Pharmaceutics
language:en
Short-container-title:International Journal of Pharmaceutics

Author:

Tang Mingtan,Lozano Hernandez Lina,Reginald-Opara Joy N.,Svirskis Darren,Leung Euphemia,Wang Hongbo,Wu Zimei

Funder

The University of Auckland Faculty of Medical and Health Sciences

Publisher

Elsevier BV

Subject

Pharmaceutical Science

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3. Binenbaum, Y., Na’ara, S., Gil, Z., Na’ara, S., Gil, Z., 2015. Gemcitabine resistance in pancreatic ductal adenocarcinoma. Drug Resist. Updat. 23, 55–68.

4. Burris III, H.A., Moore, M.J., Andersen, J., Green, M.R., Rothenberg, M.L., Modiano, M.R., et al., 1997. Improvements in survival and clinical benefit with gemcitabine as first- line therapy for patients with advanced pancreas cancer: A randomized trial. J. Clin. Oncol. 15, 2403–2413.

5. DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer;Chen;Mol. Cancer Ther.,2012

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