A new methodology for high drug loading wet granulation formulation development

Author:

Cai Lixia,Farber Leon,Zhang Dina,Li Feng,Farabaugh Julianne

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference15 articles.

1. Rheology, granule growth and granule strength: application to the wet granulation of lactose–MCC mixtures;Chitu;Powder Technol.,2011

2. Micro-mechanical properties of drying material bridges of pharmaceutical excipients;Farber;Int. J. Pharm.,2005

3. Determination of tablet strength by the diametral-compression test;Fell;J. Pharm. Sci.,1970

4. Golchert, G.D., Smales, I., Eiliazadeh, B., Musgrave, L., Razzano, E., 2006. An approach to maximise drug loading for oral tablets via formulation and process design. Poster, BPC2006.

5. A method to predict nuclei size distributions for use in models in wet granulation;Hapgood;Adv. Powder Technol.,2009

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