Statistical Design of Experiment (DoE) based development and optimization of DB213 in situ thermosensitive gel for intranasal delivery

Author:

Wang Qianwen,Wong Chun-Ho,Chan H.Y. Edwin,Lee Wai-Yip,Zuo ZhongORCID

Funder

Lui Che Woo Institute of Innovative Medicine BRAIN Initiative

Chinese University of Hong Kong

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference63 articles.

1. Evidence of nose-to-brain delivery of nanoemulsions: cargoes but not vehicles;Ahmad;Nanoscale,2017

2. Nasal in situ gel of metaproterenol sulphate; development and ex-vivo evaluation;Reena;Pharma Science Monitor,2016

3. The safety of chitosan as a pharmaceutical excipient;Baldrick;Regul. Toxicol. Pharm.,2010

4. In-situ gel formulations of econazole nitrate: preparation and in-vitro and in-vivo evaluation;Baloglu;J. Pharm. Pharmacol.,2011

5. Practical Experimental Designs and Optimization Methods for Chemists;Bayne,1986

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