Formulation development of SYN-004 (ribaxamase) oral solid dosage form, a β-lactamase to prevent intravenous antibiotic-associated dysbiosis of the colon

Author:

Bristol Andrew,Hubert Steven,Hofmann Felix,Baer Hans

Funder

Synthetic Biologics, Inc.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference20 articles.

1. Design and study of ibuprofen disintegrating sustained-release tablets comprising coated pellets;Abbaspour;Eur. J. Pharm. Biopharm.,2008

2. Clinical practice: antibiotic-associated diarrhea;Bartlett;New Engl. J. Med.,2002

3. Biology of Clostridium difficile: implications for epidemiology and diagnosis;Carroll;Annu. Rev. Microbiol.,2011

4. Degradation of β-lactam antibiotics;Deshpande;Curr. Sci.,2004

5. Antimicrobial use and risk for recurrent Clostridium difficile infection;Drekonja;Am. J. Med.,2011

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