HM10660A, a long-acting hIFN-α-2b, is a potent candidate for the treatment of hepatitis C through an enhanced biological half-life-Reference-Cited by-同舟云学术

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HM10660A, a long-acting hIFN-α-2b, is a potent candidate for the treatment of hepatitis C through an enhanced biological half-life

Published:2017-12 Issue:1-2 Volume:534 Page:89-96
ISSN:0378-5173
Container-title:International Journal of Pharmaceutics
language:en
Short-container-title:International Journal of Pharmaceutics

Author:

Bae Sungmin,Sim Taehoon,Lim Chaemin,Kim Daejin,Lee Jongsoo,Park Youngjin,Jung Sungyoub,Choi Inyoung,Kwon Sechang,Oh Kyung Taek

Funder

Korea Drug Development Fund R&D Project

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference31 articles.

1. Polyethylene glycol-conjugated pharmaceutical proteins;Bailon;Pharma. Sci. Technol. Today,1998

2. Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon α-2a for the treatment of hepatitis C;Bailon;Bioconjugate Chem.,2001

3. The binding affinity of human IgG for its high affinity Fc receptor is determined by multiple amino acids in the CH2 domain and is modulated by the hinge region;Canfield;J. Exp. Med.,1991

4. Effects of interferon-alpha (IFN-α) administration on leucocytes in healthy humans;Corssmit;Clin. Exp. Immunol.,1997

5. Monoclonal antibody clearance impact of modulating the interaction of IgG with the neonatal Fc receptor;Datta-Mannan;J. Biol. Chem.,2007

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