Predicting optimal wet granulation parameters for extrusion-spheronisation of pharmaceutical pellets using a mixer torque rheometer

Author:

Kuhs Manuel,Moore John,Kollamaram Gayathri,Walker Gavin,Croker Denise

Funder

Science Foundation Ireland (SFI)

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference21 articles.

1. Effect of microcrystalline cellulose grade and process variables on pellets prepared by extrusion–spheronization;Alvarez;Drug Dev. Ind. Pharm.,2002

2. Development and application of laboratory tools to predict particle properties upon scale-up in agitated filter-dryers;am Ende;Org. Process Res. Dev.,2013

3. On control of particle size distribution in granulation using high-shear mixers;Bardin;Powder Technol.,2004

4. Biotech, S.C., Piracetam, N.D., | CAS 7491-74-9 [WWW Document]. scbt.com. URL http://www.scbt.com/datasheet-204196-piracetam.html (Accessed 29 February 2016).

5. Understanding and avoidance of agglomeration during drying processes: a case study;Birch;Org. Process Res. Dev.,2013

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