Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase

Author:

Oda Yoshimitsu,Aryal Pramod,Terashita Takao,Gillam Elizabeth M.J,Guengerich F.Peter,Shimada Tsutomu

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference37 articles.

1. F.F. Kadlubar, G.J. Hammons, The role of cytochrome P-450 in the metabolism of chemical carcinogens, in: F.P. Guengerich (Ed.), Mammalian Cytochroms P-450, CRC Press, Boca Raton, FL, Vol. 2, 1987, pp. 81–130.

2. Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy;Guengerich;Cancer Res.,1988

3. Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes;Guengerich;Chem. Res. Toxicol.,1991

4. Role of human cytochromes P-450 in the metabolic activation of chemical carcinogens and toxins;Gonzalez;Drug Metab. Rev.,1994

5. Activation of chemically diverse procarcinogens by human cytochrome P-4501B1;Shimada;Cancer Res.,1996

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