Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus concurrent chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial

Author:

Machiels Jean-Pascal,Tao Yungan,Licitra Lisa,Burtness Barbara,Tahara Makoto,Rischin Danny,Alves Gustavo,Lima Iane Pinto Figueiredo,Hughes Brett G M,Pointreau Yoann,Aksoy Sercan,Laban Simon,Greil Richard,Burian Martin,Hetnał Marcin,Delord Jean-Pierre,Mesía Ricard,Taberna Miren,Waldron John N,Simon Christian,Grégoire Vincent,Harrington Kevin J,Swaby Ramona F,Zhang Yayan,Gumuscu Burak,Bidadi Behzad,Siu Lillian L,Rischin Danny,Hughes Brett GM,Gao Bo,McGrath Margaret,Greil Richard,Thurnher Dietmar,Fuereder Thorsten,Burian Martin,Rottey Sylvie,Machiels Jean-Pascal,Clement Paul M,Henry Stéphanie,Deheneffe Stéphanie,Vasconcelos Alves Gustavo,Lima Iane Pinto Figueiredo,Mourão Dias Josiane,De Marchi Pedro Rafael Martins,Mak Milena Perez,Pereira de Santana Gomes Andrea Juliana,Oliveira de Castro Junior Dalvaro,Motta Tatiane Cardoso,Agostinho Padoan Monica Luciana,Victorina Ana Paula,de Azevedo Sergio Jobim,Siu Lillian L,Brule Stephanie,Hilton John,Wang Chang Shu,Bouganim Nathaniel,Webster Marc,Walker John,Chua Neil,Zambrano Angela Regina,Quiroga Echeverri Alicia,Niño Gomez Oscar Mauricio,Ortiz Carlos Alberto,Rojas Luis,Cardona Zorilla Andrés,Urrego Meléndez Olga Marcela,Holečková Petra Beran,Melichar Bohuslav,Cvek Jakub,Prausová Jana,Vošmik Milan,Delord Jean-Pierre,Zasadny Xavier,Geoffrois Lionnel,Tao Yungan,Pointreau Yoann,Fietkau Rainer,Haderlein Marlen,Mueller Andreas H,Schroeder Ursula,Wollenberg Barbara,Laban Simon,Ivanyi Philipp,Gruenwald Viktor,Schafhausen Philippe,Gutfeld Orit,Gluck Iris,Popovtzer Aron,Meirovitz Amichay,Billan Salem,Brenner Baruch,Popovtzer Aron,Limon Dror,Licitra Lisa,Perri Francesco,Caponigro Francesco,Violati Martina,Ferrari Daris,Nole Franco,Bertolini Federica,Livi Lorenzo,Ghi Maria Grazia,Imarisio Ilaria,Tahara Makoto,Homma Akihiro,Ueda Tsutomu,Asada Yukinori,Yamazaki Tomoko,Matsumoto Koji,Fujii Takashi,Ikeda Sadakatsu,Takahashi Shunji,Kinoshita Takashi,Sasaki Keita,Tsuji Akihito,Ahn Myung-Ju,Cho Byoung Chul,Lee Keun-Wook,Lee Ki Hyeong,Choi Moon Ki,Yun Hwan Jung,Hendriks Mathijs P,Oosting Sjoukje F,Buter Jan,Van Meerten Esther,Graham Jonathan,Kawecki Andrzej,Debicka Izabella,Maciejczyk Adam,Pysz Maciej,Filarska Dorota,Hetnał Marcin,Koralewski Piotr,Wygoda Andrzej,Składowski Krzysztof,Talerczyk Małgorzata,Berrocal Jaime Alfonso,Pérez Segura Pedro,Braña García Irene,Basté Rotllan Neus,Mesía Nin Ricard,Taberna Sanz Miren,Iglesias Docampo Lara,Soria Rivas Ainara,Rueda Domínguez Antonio,Trigo Pérez José Manuel,Hong Ruey-Long,Li Shau-Hsuan,Wang Hung-Ming,Yen Chia-Jui,Yang Muh-Hwa,Chang Yi-Fang,Liu Yi-Chun,Lin Jin-Ching,Ekenel Meltem,Harputluoğlu Hakan,Aksoy Sercan,Özyilkan Özgür,Bılıcı Ahmet,Şendur Mehmet Alı Nahıt,Arslan Cagatay,Harrington Kevin,Ramkumar Shanmugasundaram,Gujral Dorothy,Stewart Simon,Powell Melanie,Sibtain Amen,Roques Tom,Yip Kent,Mirza Arafat,Sivaramalingam Muthiah,Belman Neil D,Agarwala Sanjiv,Anderson Ian,Patel Arpan,Maggiore Ronald,Baumgart Megan,Burtness Barbara,Fidler Mary Jo,Kaur Varinder,Gaughan Elizabeth,Worden Francis,Rodriguez Cristina P,Sukari Ammar,Wong Deborah,Yom Sue,Walsh William V,Fiorillo Joseph A,Yorio Jeffrey T,Obara Grzegorz S

Funder

Merck Sharp and Dohme United Kingdom

Publisher

Elsevier BV

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