Durvalumab, with or without tremelimumab, plus platinum–etoposide versus platinum–etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): updated results from a randomised, controlled, open-label, phase 3 trial

Author:

Goldman Jonathan W,Dvorkin Mikhail,Chen Yuanbin,Reinmuth Niels,Hotta Katsuyuki,Trukhin Dmytro,Statsenko Galina,Hochmair Maximilian J,Özgüroğlu Mustafa,Ji Jun Ho,Garassino Marina Chiara,Voitko Oleksandr,Poltoratskiy Artem,Ponce Santiago,Verderame Francesco,Havel Libor,Bondarenko Igor,Każarnowicz Andrzej,Losonczy György,Conev Nikolay V,Armstrong Jon,Byrne Natalie,Thiyagarajah Piruntha,Jiang Haiyi,Paz-Ares Luis,Dvorkin Mikhail,Trukhin Dmytro,Statsenko Galina,Voitko Nataliia,Poltoratskiy Artem,Bondarenko Igor,Chen Yuanbin,Kazarnowicz Andrzej,Paz-Ares Luis,Özgüroglu Mustafa,Conev Nikolay,Hochmair Maximilian,Burghuber Otto,Havel Libor,Çiçin Irfan,Losonczy György,Moiseenko Vladimir,Erman Mustafa,Kowalski Dariusz,Wojtukiewicz Marek,Adamchuk Hryhoriy,Vasilyev Alexander,Shevnia Serhii,Valev Spartak,Reinmuth Niels,Ji Jun Ho,Insa Molla Maria Amelia,Ursol Grygorii,Chiang Anne,Hartl Sylvia,Horváth Zsolt,Pajkos Gábor,Verderame Francesco,Hotta Katsuyuki,Kim Sang-We,Smolin Alexey,Göksel Tuncay,Dakhil Shaker,Roubec Jaromir,Bogos Krisztina,Garassino Marina Chiara,Cornelissen Robin,Lee Jong-Seok,Garcia Campelo Maria Rosario,Lopez Brea Marta,Alacacioglu Ahmet,Casarini Ignacio,Ilieva Rumyana,Tonev Ivan,Somfay Attila,Bar Jair,Zer Kuch Alona,Minelli Mauro,Bartolucci Roberta,Roila Fausto,Saito Haruhiro,Azuma Koichi,Lee Gyeong-Won,Luft Alexander,Urda Michal,Delgado Mingorance Juan Ignacio,Majem Tarruella Margarita,Spigel David,Koynov Krassimir,Zemanova Milada,Panse Jens,Schulz Christian,Pápai Székely Zsolt,Sárosi Veronika,Delmonte Angelo,Bettini Anna Cecilia,Nishio Makoto,Okamoto Isamu,Hendriks Lizza,Mandziuk Slawomir,Lee Yun Gyoo,Vladimirova Lyubov,Isla Casado Dolores,Domine Gomez Manuel,Navarro Mendivil Alejandro,Morán Bueno Teresa,Wu Shang-Yin,Knoble Jeanna,Skrickova Jana,Venkova Violetka,Hilgers Werner,Laack Eckart,Bischoff Helge,Fülöp Andrea,Laczó Ibolya,Kósa Judit,Telekes András,Yoshida Tatsuya,Kanda Shintaro,Hida Toyoaki,Hayashi Hidetoshi,Maeda Tadashi,Kawamura Tetsuji,Nakahara Yasuharu,Claessens Niels,Lee Ki Hyeong,Chiu Chao-Hua,Lin Sheng-Hao,Li Chien-Te,Demirkazik Ahmet,Schaefer Eric,Nikolinakos Petros,Schneider Jeffrey,Babu Sunil,Lamprecht Bernd,Studnicka Michael,Fausto Nino Gorini Carlos,Kultan Juraj,Kolek Vitezslav,Souquet Pierre-Jean,Moro-Sibilot Denis,Gottfried Maya,Smit Egbert,Lee Kyung Hee,Kasan Peter,Chovanec Jozef,Goloborodko Olexandr,Kolesnik Oleksii,Ostapenko Yuriy,Lakhanpal Shailendra,Haque Basir,Chua Winston,Stilwill Joseph,Sena Susana Noemi,Girotto Gustavo Colagiovanni,De Marchi Pedro Rafael Martins,Martinelli de Oliveira Fabricio Augusto,Dos Reis Pedro,Krasteva Rositsa,Zhao Yanqiu,Chen Chengshui,Koubkova Leona,Robinet Gilles,Chouaid Christos,Grohe Christian,Alt Jürgen,Csánky Eszter,Somogyiné Ezer Éva,Heching Norman Isaac,Kim Young Hak,Aatagi Shinji,Kuyama Shoichi,Harada Daijiro,Nogami Naoyuki,Nokihara Hiroshi,Goto Hisatsugu,Staal van den Brekel Agnes,Cho Eun Kyung,Kim Joo-Hang,Ganea Doina,Ciuleanu Tudor,Popova Ekaterina,Sakaeva Dina,Stresko Marian,Demo Pavol,Godal Robert,Wei Yu-Feng,Chen Yen-Hsun,Hsia Te-Chun,Lee Kang-Yun,Chang Huang-Chih,Wang Chin-Chou,Dowlati Afshin,Sumey Christopher,Powell Steven,Goldman Jonathan,Zarba Juan Jose,Batagelj Emilio,Pastor Andrea Viviana,Zukin Mauro,Baldotto Clarissa Serodio da Rocha,Schlittler Luis Alberto,Calabrich Aknar,Sette Claudia,Dudov Asen,Zhou Caicun,Lena Hervé,Lang Susanne,Pápai Zsuzsanna,Goto Koichi,Umemura Shigeki,Kanazawa Kenya,Hara Yu,Shinoda Masahiro,Morise Masahiro,Hiltermann Jeroen,Mróz Robert,Ungureanu Andrei,Andrasina Igor,Chang Gee-Chen,Vynnychenko Ihor,Shparyk Yaroslav,Kryzhanivska Anna,Ross Helen,Mi Kailhong,Jamil Rodney,Williamson Michael,Spahr Joseph,Han Zhigang,Wang Mengzhao,Yang Zhixiong,Hu Jie,Li Wei,Zhao Jun,Feng Jifeng,Ma Shenglin,Zhou Xiangdong,Liang Zongan,Hu Yi,Chen Yuan,Bi Minghong,Shu Yongqian,Nan Kejun,Zhou Jianying,Zhang Wei,Ma Rui,Yang Nong,Lin Zhong,Wu Gang,Fang Jian,Zhang Helong,Wang Kai,Chen Zhendong

Funder

AstraZeneca

Publisher

Elsevier BV

Subject

Oncology

Reference29 articles.

1. What's new in SCLC? A review;Oronsky;Neoplasia,2017

2. Survival changes in patients with small cell lung cancer and disparities between different sexes, socioeconomic statuses and ages;Wang;Sci Rep,2017

3. Small cell lung cancer: where do we go from here?;Byers;Cancer,2015

4. Pembrolizumab versus ipilimumab in advanced melanoma;Robert;N Engl J Med,2015

5. Nivolumab in previously untreated melanoma without BRAF mutation;Robert;N Engl J Med,2015

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