EMD 68843, a serotonin reuptake inhibitor with selective presynaptic 5-HT1A receptor agonistic properties

Author:

Bartoszyk Gerd D,Hegenbart Rainer,Ziegler Herbert

Publisher

Elsevier BV

Subject

Pharmacology

Reference49 articles.

1. Albert, P.R., P. Lembo, J.M. Storring, A. Charest and C. Saucier, 1996, The 5-HT1A receptor: signalling, desensitization, and gene transcription, Neuropsychopharmacology 14, 19.

2. Artigas, F., V. Perez and E. Alvarez, 1994, Pindolol induces a rapid improvement of patients with depression treated with serotonin reuptake inhibitors, Arch. Gen. Psychiatry 51, 248.

3. Auerbach, S.B., J.F. Lundberg and S. Hjorth, 1995, Differential inhibition of serotonin release by 5-HT and NA blockers after systemic administration, Neuropharmacology 34, 89.

4. Bartoszyk, G.D., A. Barber, H. Böttcher, H.E. Greiner, J. Leibrock, J.M. Martı́nez and C.A. Seyfried, 1996, Pharmacological profile of the mixed 5HT-reuptake inhibitor/5HT1A-agonist EMD 68843, Soc. Neurosci. Abstr. 22, 613.

5. Bergeron, R., C. De Montigny and P. Blier, 1995, Selective activation of postsynaptic serotonin1A receptors may induce a rapid antidepressant response, Psychopharmacol. Bull. 31, 523.

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