In vitro and in vivo m2 muscarinic subtype selectivity of some dibenzodiazepinones and pyridobenzodiazepinones

Author:

Cohen Victor I,Jin Biyun,McRee R.Carter,Boulay Sheila F,Cohen Emil I,Sood Virendar K,Zeeberg Barry R,Reba Richard C

Publisher

Elsevier BV

Subject

Developmental Biology,Neurology (clinical),Molecular Biology,General Neuroscience

Reference49 articles.

1. Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease;Araujo;J. Neurochem.,1988

2. Comparative alterations of nicotinic and muscarinic binding sites in Alzheimer's and Parkinson's diseases;Aubert;J. Neurochem.,1992

3. Characterization and autoradiographic distribution of [3H]AF-DX 384 binding to putative muscarinic M2 receptors in the rat brain;Aubert;Eur. J. Pharmacol.,1992

4. Comparison of the in vivo rat brain regional pharmacokinetics of [3H]QNB, (R,S)-[125I]-4IQNB, and (R,R)-[125I]-4IQNB binding to the muscarinic acetylcholine receptor in relationship to the regional subtype composition;Boulay;Receptor,1996

5. Autoradiographic evidence that 3-quinuclidinyl 4-fluorobenzilate (FQNB) displays in vivo selectivity for the m2 subtype;Boulay;NeuroImage,1996

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