Development of genotoxicity test procedures with Episkin®, a reconstructed human skin model: Towards new tools for in vitro risk assessment of dermally applied compounds?

Author:

Flamand Nicole,Marrot Laurent,Belaidi Jean-Philippe,Bourouf Linda,Dourille Emilie,Feltes Michèle,Meunier Jean-Roch

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference60 articles.

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3. COM, Guidance on a strategy for testing of chemicals for mutagenicity. Committee on mutagenicity of chemicals in food, consumer products and the environment, 2000.

4. SCCNFP, Recommended mutagenicity/genotoxicity test for the sefaty testing of cosmetic ingredients to be included in the annexes to council directive 76/768/EEC. SCCNFP/0755/03, 2004.

5. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity;Kirkland;Mutat. Res.,2005

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