High-specificity and high-sensitivity genotoxicity assessment in a human cell line: Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay

Author:

Hastwell Paul W.,Chai Li-Leng,Roberts Kevin J.,Webster Thomas W.,Harvey James S.,Rees Robert W.,Walmsley Richard M.

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference47 articles.

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2. ICH, Topic S2A. Genotoxicity: Guidance on Specific Aspects of Regulatory Genotoxicity Tests for Pharmaceuticals (1996). http://www.emea.eu.int/pdfs/human/ich/014195en.pdf.

3. Assessment of the performance of the Ames II(TM) assay: a collaborative study with 19 coded compounds;Fluckiger-Isler;Mutat. Res.: Genet. Toxicol. Environ. Mut.,2004

4. Increase of sensitivity and validity of the SOS/umu-test after replacement of the [beta]-galactosidase reporter gene with luciferase;Schmid;Mutat. Res.: Genet. Toxicol. Environ. Mut.,1997

5. Development of a green fluorescent protein reporter for a yeast genotoxicity biosensor;Billinton;Biosens. Bioelectron.,1998

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