In silico assessment of chemical mutagenesis in comparison with results of Salmonella microsome assay on 909 chemicals

Author:

Hayashi Makoto,Kamata Eiichi,Hirose Akihiko,Takahashi Mika,Morita Takeshi,Ema Makoto

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference13 articles.

1. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. I. Sensitivity, specificity and relative predictivity;Kirkland;Mutat. Res.,2005

2. Law Concerning the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc., Law No. 117, 16 October 1973 as last amended by Law No.49, 28 May 2003.

3. Use of QSARs in international decision-making frameworks to predict health effects of chemical substances;Cronin;Environ. Health Perspect.,2003

4. Integration of computational analysis as sentinel tool in toxicological assessments;Pearl;Curr. Topoics Med. Chem.,2001

5. Development of genotoxicity predicting QSAR system for registered and existing industrial chemicals in Japan;Hirose;Toxicol. Appl. Pharmacol.,2004

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