IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs)

Author:

MacGregor James T.,Frötschl Roland,White Paul A.,Crump Kenny S.ORCID,Eastmond David A.,Fukushima Shoji,Guérard Melanie,Hayashi Makoto,Soeteman-Hernández Lya G.,Kasamatsu Toshio,Levy Dan D.,Morita Takeshi,Müller Lutz,Schoeny RitaORCID,Schuler Maik J.,Thybaud Véronique,Johnson George E.ORCID

Funder

National Centre for the Replacement, Refinement and Reduction of Animals in Research

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference68 articles.

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2. Summary of major conclusions from the 4th IWGT, San Francisco, 9–10 September, 2005;Kirkland;Mutat. Res.,2007

3. Strategies in case of positive in vivo results in genotoxicity testing;Thybaud;Mutat. Res.,2011

4. Reflections on the origins and evolution of genetic toxicology and the Environmental Mutagen Society;Wassom;Environ. Mol. Mutagen.,2010

5. Standards for Mutagenicity Tests using Microorganisms, Notification based on Article 57-2-1 of the Industrial Safety and Health Law, Ordinance No. 57;Ministry of Labour, Japan,1972

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