New DNA probes to detect aneugenicity in rat bone marrow micronucleated cells by a pan-centromeric FISH analysis

Author:

Takeiri Akira,Motoyama Shigeki,Matsuzaki Kaori,Harada Asako,Taketo Junko,Katoh Chiaki,Tanaka Kenji,Mishima Masayuki

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference34 articles.

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2. Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (Groups 1, 2A and 2B)

3. In vivo rodent micronucleus assay: protocol, conduct and data interpretation;Krishna;Mutat. Res.,2000

4. Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons;Mäki-Paakkanen;Mutagenesis,1995

5. ICH Harmonised Tripartite Guideline, Guidance on Genotoxicity Testing and Data Interpretation for Pharmaceuticals Intended for Human Use S2(R1) Step 4;ICH Steering Committee,2011

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