Etoposide, cadmium chloride, benzo[a]pyrene, cyclophosphamide and colchicine tested in the in vitro mammalian cell micronucleus test (MNvit) in the presence and absence of cytokinesis block using L5178Y mouse lymphoma cells and 2-aminoanthracene tested in MNvit in the absence of cytokinesis block using TK6 cells at AstraZeneca UK, in support of OECD draft Test Guideline 487-Reference-Cited by-同舟云学术

Etoposide, cadmium chloride, benzo[a]pyrene, cyclophosphamide and colchicine tested in the in vitro mammalian cell micronucleus test (MNvit) in the presence and absence of cytokinesis block using L5178Y mouse lymphoma cells and 2-aminoanthracene tested in MNvit in the absence of cytokinesis block using TK6 cells at AstraZeneca UK, in support of OECD draft Test Guideline 487

Published:2010-10 Issue:2 Volume:702 Page:163-170
ISSN:1383-5718
Container-title:Mutation Research/Genetic Toxicology and Environmental Mutagenesis
language:en
Short-container-title:Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Author:

Fellows Michael D.,O’Donovan Michael R.

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference7 articles.

1. D. Kirkland, Evaluation of Different Cytotoxicity Measures for the In Vitro Micronucleus Test (MNVit): Introduction to the Collaborative Trial, this issue.

2. OECD (Draft), OECD Guideline for Testing of Chemicals. No. 487: In Vitro Mammalian Cell Micronucleus Test (MNvit), available: [http://www.oecd.org/document/55/0,3343, en_2649_34377_2349687_1_1_1_1,00.html].

3. Cytogenetic analysis of the L5178Y/TK+/− mouse lymphoma mutagenesis assay system;Hozier;Mutat. Res.,1998

4. Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test 1;Lorge;Mutat. Res.,2008

5. Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test. II. Practical aspects with toxic agents;Fellows;Mutat. Res.,2008

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