Induction of micronuclei in mouse bone-marrow erythrocytes in association with hypothermia after administration of the sigma receptor ligand E-5842

Author:

Guzmán Antonio,García Concepción,Marín Ana-Paz,Ruiz Maria Teresa,Tortajada Araceli,de Henestrosa Antonio R. Fernández

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference49 articles.

1. ICH-S2B, ICH Topic S2B Genotoxicity: a Standard Battery for Genotoxicity Testing of Pharmaceuticals. Step 4, 1-9-1997.

2. E-5842: a new potent and preferential sigma ligand. Preclinical pharmacological profile, CNS;Guitar;Drug. Rev.,1998

3. ICH-S2A, ICH Topic S2A Genotoxicity: Guidance on Specific Aspects of Regulatory Genotoxicity Tests for Pharmaceuticals. Step 5, 1-9-1995.

4. DNA synthesis inhibition as an indirect mechanism of chromosome aberrations: comparison of DNA-reactive and non-DNA-reactive clastogens;Galloway;Mutat. Res.,1998

5. Genotoxicity under extreme culture conditions. A report from ICPEMC Task Group 9;Scott;Mutat. Res.,1991

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