Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing

Author:

Marchetti Francesco,Aardema Marilyn J.,Beevers Carol,van Benthem JanORCID,Godschalk Roger,Williams Andrew,Yauk Carole L.,Young Robert,Douglas George R.

Funder

Health and Environmental Sciences Institute. Washington, DC, USA

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference92 articles.

1. Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488;Marchetti;Mutat. Res.Genet. Toxicol. Environ. Mutagenesis,2018

2. Declaring the existence of human germ-cell mutagens;DeMarini;Environ. Mol. Mutagen,2012

3. Approaches for identifying germ cell mutagens: report of the 2013 IWGT workshop on germ cell assays;Yauk;Mutat. Res. Genet. Toxicol. Environ. Mutagen,2015

4. Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assay, OECD Guidelines for Testing of Chemicals, Section 4;OECD,2013

5. Detailed review of transgenic rodent mutation assays;Lambert;Mutat. Res.,2005

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