A practical synthesis of the ω side-chain unit present in mexiprostil and its use for synthesis of mexiprostil via two-component coupling process.
Author:
Publisher
Elsevier BV
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis
Reference15 articles.
1. Structure-activity studies of 16-methoxy-16-methyl prostaglandins
2. X-ray structure determination of mexiprostil, A new gastroprotective 16-methoxy-16-methyl-PGE1 analogue
3. A highly convergent synthesis of mexiprestil: 16(R) 16-methoxy 16-methyl PGE1 methyl ester
4. A practical procedure for the conversion of aldehydes to terminal alkynes by a one carbon homologation
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1. ChemInform Abstract: A Practical Synthesis of the ω Side-Chain Unit Present in Mexiprostil and Its Use for Synthesis of Mexiprostil via Two-Component Coupling Process.;ChemInform;2010-08-23
2. Synthesis of 2-Normisoprostol, Methyl 6-(3-Hydroxy-2-((E)-4-hydroxy-4-methyloct-1-enyl)-5-oxocyclopentyl)hexanoate;Synthetic Communications;2009-07-07
3. Fully Stereocontrolled Syntheses of 3-Oxacarbacyclin and Carbacyclin by the Conjugate Addition-Azoalkene-Asymmetric Olefination Strategy;The Journal of Organic Chemistry;2006-05-17
4. Prostaglandin Synthesis via Two-Component Coupling Process: The Course of Industry-University Cooperation toward the Production of PGE1 in a Kilogram Scale.;Journal of Synthetic Organic Chemistry, Japan;1999
5. A highly efficient approach to prostaglandins via radical addition of α side-chains to methylenecyclopentanones. Total synthesis of natural PGE1, limaprost and new prostaglandin derivatives.;Tetrahedron Letters;1993-10
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