Chemoenzymatic synthesis2 of both enantiomers of fluoxetine, tomoxetine and nisoxetine: lipase-catalyzed resolution of 3-aryl-3-hydroxypropanenitriles

Author:

Kamal Ahmed,Khanna G.B.Ramesh,Ramu R.

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Reference93 articles.

1. Molloy, B. B.; Schmiegel, K. K. Ger. Pat. 2,500,110; US pat. 4,314,081

2. Klaus Florey. Analytical profiles of Drug Substances; Academic Press: San Diego, 1990; Vol. 19, pp. 193–219 and references cited therein

3. Fluoxetine in Patients with Major Depressive Disorder - A Responder Analysis

4. Prozac (fluoxetine, lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: Twenty years since its first publication

5. Foster, B. J.; Lavangnino, E. R. EP 52,492; GB 2,087,883; JP 82,114,555

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