A combinatorial approach for determining protease specificities: application to interleukin-1β converting enzyme (ICE)

Author:

Rano Thomas A.,Timkey Tracy,Peterson Erin P.,Rotonda Jennifer,Nicholson Donald W.,Becker Joseph W.,Chapman Kevin T.,Thornberry Nancy A.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference40 articles.

1. Substrate phage: selection of protease substrates by monovalent phage display;Matthews;Science,1993

2. A survey of form substrate specificity using substrate phage display;Matthews;Proc. Science,1994

3. Rapid identification of highly active and selective substrates for stromelysin and matrilysin using bacteriophage peptide display libraries;Smith;J. Biol. Chem.,1995

4. Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endoprotease specificity;Meldal,1994

5. A rapid method for determination of endoproteinase substrate specificity: Specificity of the 3C proteinase from hepatitis A virus;Petithory,1991

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