Development of an on-line coupling of liquid–liquid extraction, normal-phase liquid chromatography and high-resolution gas chromatography producing an analytical marker for the prediction of mutagenicity and carcinogenicity of bitumen and bitumen fumes

Author:

Blomberg Jan,de Groot Paul C,Brandt Henk C.A,van der Does Jan J.B,Schoenmakers Peter J

Publisher

Elsevier BV

Subject

Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry

Reference16 articles.

1. Comparison of PAC Analysis with Biological Activity for Bitumen Fume Condensates

2. Selective Determination of Potentially Hazardous Polycyclic Aromatics in Luboil Fractions by the DMSO Extraction Method – Its Development, Evaluation and Use;van der Wiel,1993

3. IP346/92(98), Polycyclic Aromatics in Unused Lubricating Base Oils and Asphaltene Free Petroleum Fractions — Dimethyl Sulphoxide Extraction Refractive Index Method (ST-G-2),1998

4. CONCAWE Report No. 98/54, Classification and Labelling of Petroleum Substances According to the EU Dangerous Substances Directive (revision 1), Appendix 5, CONCAWE, Brussels, 1998.

5. Correlation of mutagenic and dermal carcinogenic activities of mineral oils with polycyclic aromatic compound content*1

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