Separation of HI-6 [4-carbamoyl-2′-hydroxyiminomethyl-1,1′-oxydimethylen-di(pyridinium chloride)] and its degradation products by ion-pair high-performance liquid chromatography
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry
Reference13 articles.
1. Absorption and excretion of pralidoxime in man after intramuscular injection of PAM-2CL and various cholinolytics
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3. Ion-pair high-performance liquid chromatographic separation of multicomponent anticholinergic drug formulation
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1. A novel high‐performance liquid chromatography with diode array detector method for the simultaneous quantification of the enzyme‐reactivating oximes obidoxime, pralidoxime, and HI‐6 in human plasma;Drug Testing and Analysis;2020-04-23
2. In memory of Ilse Hagedorn;Toxicology;2007-04
3. Degradation of Three Related Bis(Pyridinium)Aldoximes in Aqueous Solutions at High Concentrations: Examples of Unexpectedly Rapid Amide Group Hydrolysis;Journal of Pharmaceutical Sciences;1993-08
4. Kinetic determination of 1-{[4′-(aminocarbonyl)-1′-pyridinio]-methoxymethyl}-2-(hydroxyiminomethyl)pyridinium dichloride (HI-6) alone and in binary mixtures with 1,1′-(oxydimethylene)bis(4-hydroxyiminomethylpyridinium) dichloride (toxogonin) and 1,1′-(propane-1,3-diyl)bis(4-hydroxyiminomethylpyridinium) dibromide (TMB-4);The Analyst;1990
5. Thermospray mass spectrometry of diquaternary pyridinium oxime salts;Biological Mass Spectrometry;1988-09
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