1. The concepts introduced in this article are those I feel are of importance when studying lung immune defence systems. I take full responsibility for the more “debatable” points raised. The overview is based on information gained from the work of my own group to whom I am constantly grateful but I have also leant heavily on the following articles in which the original observations I quote are all referenced.
2. Anatomical environment as a determinant in viral immunity;Doherty;J. Immunol.,1995
3. An important role for intestinally derived T cells in respiratory defence;Dunkley;Immunol. Today,1995
4. The surfactant system of the adult lung; physiology and clinical perspectives;Hamm;Clin. Invest.,1992
5. Pulmonary immune cells in health and disease, the eosinophil leucocyte (part 1);Kroegel;Eur. Respir. J.,1994