Use of chelating agents to improve the resolution and consistency of cation-exchange chromatography of monoclonal antibodies
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry
Reference18 articles.
1. Chromatographic analysis of the acidic and basic species of recombinant monoclonal antibodies;Du;mAbs,2012
2. Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods;Vlasak;Curr. Pharm. Biotechnol.,2010
3. Heterogeneity of monoclonal antibodies;Liu;J. Pharm. Sci.,2008
4. Mass spectrometry for structural characterization of therapeutic antibodies;Zhang;Mass Spectrom. Rev.,2009
5. Reversible interference of Fe3+ with monoclonal antibody analysis in cation exchange columns;Rao;Anal. Biochem.,2011
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Effects of carboxypeptidase B treatment and elevated temperature on recombinant monoclonal antibody charge variants in cation-exchange chromatography analysis;Archives of Pharmacal Research;2016-08-13
2. Unfolding and aggregation of monoclonal antibodies on cation exchange columns: Effects of resin type, load buffer, and protein stability;Journal of Chromatography A;2015-04
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