Modeling and simulation of protein elution in linear pH and salt gradients on weak, strong and mixed cation exchange resins applying an extended Donnan ion exchange model-Reference-Cited by-同舟云学术

Modeling and simulation of protein elution in linear pH and salt gradients on weak, strong and mixed cation exchange resins applying an extended Donnan ion exchange model

Published:2018-04 Issue: Volume:1545 Page:32-47
ISSN:0021-9673
Container-title:Journal of Chromatography A
language:en
Short-container-title:Journal of Chromatography A

Author:

Wittkopp Felix,Peeck Lars,Hafner Mathias,Frech Christian

Funder

Merck KGaA

Publisher

Elsevier BV

Subject

Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry

Reference94 articles.

1. Fresh from the biotech pipeline – 2016;Morrison;Nat. Biotech.,2017

2. Therapeutic monoclonal antibodies and derivatives: historical perspectives and future directions;Rodgers;Biotechnol. Adv.,2016

3. Chromatographic media for bioseparation;Jungbauer;J. Chromatogr. A,2005

4. State-of-the-art in downstream processing of monoclonal antibodies: process trends in design and validation;Marichal-Gallardo;Biotechnol. Progr.,2012

5. Identification and characterization of host cell protein product-associated impurities in monoclonal antibody bioprocessing;Levy;Biotechnol. Bioeng.,2014

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Concepts and milestones in the development of ion-exchange chromatography;Ion-Exchange Chromatography and Related Techniques;2024

2. Two peak elution behavior of a monoclonal antibody in cation exchange chromatography as a screening tool for excipients;Journal of Chromatography B;2023-01

3. A novel lipid droplets‐targeting fluorescent probe based on dicyanisophorone and carbazole for Cu ²⁺ and its application;Journal of the Chinese Chemical Society;2022-12-27

4. Influence of ligand density variations on the two peak elution behavior of a monoclonal antibody in cation exchange chromatography;Journal of Chromatography A;2022-09

5. Calculation of the Gibbs–Donnan factors for multi-ion solutions with non-permeating charge on both sides of a permselective membrane;Scientific Reports;2021-11-12