Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part II. Protein structure effects by hydrogen deuterium exchange mass spectrometry

Author:

Guo Jing,Carta Giorgio

Funder

NSF

Amgen

Publisher

Elsevier BV

Subject

Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry

Reference28 articles.

1. Effects of protein aggregates: an immunologic perspective;Rosenberg;AAPS J.,2006

2. The development of stable protein formulations - a close look at protein aggregation, deamidation, and oxidation;Cleland;Crit. Rev. Therap. Drug Carr. Syst.,1993

3. Kinetics of unfolding of proteins on hydrophobic surfaces in reversed-phase liquid-chromatography;Benedek;J. Chromatogr.,1984

4. Conformational effects in the high-performance liquid-chromatography of proteins - further-studies of the reversed-phase chromatographic behavior of ribonuclease-a;Lu;J. Chromatogr.,1986

5. The effect of on-column structural-changes of proteins on their hplc behavior;Karger;Talanta,1989

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