Post-pellet-digestion precipitation and solid phase extraction: A practical and efficient workflow to extract surrogate peptides for ultra-high performance liquid chromatography – tandem mass spectrometry bioanalysis of a therapeutic antibody in the low ng/mL range
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry
Reference29 articles.
1. Bioanalytical LC–MS/MS of protein-based biopharmaceuticals;van den Broek;J. Chromatogr. B: Anal. Technol. Biomed. Life Sci.,2013
2. Monoclonal antibodies: what are the pharmacokinetic and pharmacodynamic considerations for drug development?;Deng;Expert Opin. Drug Metab. Toxicol.,2012
3. Innovative use of LC–MS/MS for simultaneous quantitation of neutralizing antibody, residual drug, and human immunoglobulin G in immunogenicity assay development;Jiang;Anal. Chem.,2014
4. Fully validated LC–MS/MS assay for the simultaneous quantitation of coadministered therapeutic antibodies in cynomolgus monkey serum;Jiang;Anal. Chem.,2013
5. Development of a validated liquid chromatography tandem mass spectrometry assay for a PEGylated adnectin in cynomolgus monkey plasma using protein precipitation and trypsin digestion;Dawes;J. Chromatogr. B: Anal. Technol. Biomed. Life Sci.,2013
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