Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5-Reference-Cited by-同舟云学术

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Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5

Published:2019-05 Issue:5 Volume:12 Page:906-919
ISSN:2213-6711
Container-title:Stem Cell Reports
language:en
Short-container-title:Stem Cell Reports

Author:

Quinn Peter M.,Buck Thilo M.,Mulder Aat A.,Ohonin Charlotte,Alves C. Henrique,Vos Rogier M.,Bialecka Monika,van Herwaarden Tessa,van Dijk Elon H.C.,Talib Mays,Freund Christian,Mikkers Harald M.M.,Hoeben Rob C.,Goumans Marie-José,Boon Camiel J.F.,Koster Abraham J.,Chuva de Sousa Lopes Susana M.,Jost Carolina R.,Wijnholds Jan

Funder

Foundation Fighting Blindness

Netherlands Organisation for Health Research and Development

Curing Retinal Blindness Foundation

Stichting Retina Fonds

Landelijke Stichting voor Blinden en Slechtzienden

Rotterdamse Stichting Blindenbelangen

Stichting Blindenhulp

MaculaFonds

LUMC

Publisher

Elsevier BV

Subject

Cell Biology,Developmental Biology,Genetics,Biochemistry

Reference49 articles.

1. GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors;Aartsen;PLoS One,2010

2. Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene;Alves;Hum. Mol. Genet.,2013

3. The CRB1 and adherens junction complex proteins in retinal development and maintenance;Alves;Prog. Retin. Eye Res.,2014

4. Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa;Alves;Hum. Mol. Genet.,2014

5. The AAV vector toolkit: poised at the clinical crossroads;Asokan;Mol. Ther.,2012

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