Genome Toxicity and Impaired Stem Cell Function after Conditional Activation of CreERT2 in the Intestine-Reference-Cited by-同舟云学术

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Genome Toxicity and Impaired Stem Cell Function after Conditional Activation of CreERT2 in the Intestine

Published:2018-12 Issue:6 Volume:11 Page:1337-1346
ISSN:2213-6711
Container-title:Stem Cell Reports
language:en
Short-container-title:Stem Cell Reports

Author:

Bohin Natacha,Carlson Elizabeth A.,Samuelson Linda C.

Funder

Cellular and Molecular Biology program

Rackham research grant

NIH

Publisher

Elsevier BV

Subject

Cell Biology,Developmental Biology,Genetics,Biochemistry

Reference25 articles.

1. Identification of stem cells in small intestine and colon by marker gene Lgr5;Barker;Nature,2007

2. Gene targeting in mice: a review;Bouabe;Methods Mol. Biol.,2013

3. Crypt stem cell survival in the mouse intestinal epithelium is regulated by prostaglandins synthesized through cyclooxygenase-1;Cohn;J. Clin. Invest.,1997

4. Direct hematological toxicity and illegitimate chromosomal recombination caused by the systemic activation of CreERT2;Higashi;J. Immunol.,2009

5. Inducible activation of Cre recombinase in adult mice causes gastric epithelial atrophy, metaplasia, and regenerative changes in the absence of “floxed” alleles;Huh;Am. J. Physiol. Gastrointest. Liver Physiol.,2010

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2. Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells;Cell;2024-06

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