Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-risking-Reference-Cited by-同舟云学术

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Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-risking

Published:2018-12 Issue:6 Volume:11 Page:1365-1377
ISSN:2213-6711
Container-title:Stem Cell Reports
language:en
Short-container-title:Stem Cell Reports

Author:

Kopljar Ivan,Lu Hua Rong,Van Ammel Karel,Otava Martin,Tekle Fetene,Teisman Ard,Gallacher David J.

Funder

Innovative Medicines Initiative

European Union's Seventh Framework Programme

EFPIA

Publisher

Elsevier BV

Subject

Cell Biology,Developmental Biology,Genetics,Biochemistry

Reference33 articles.

1. A new paradigm for drug-induced torsadogenic risk assessment using human iPS cell-derived cardiomyocytes;Ando;J. Pharmacol. Toxicol. Methods,2017

2. High-throughput drug profiling with voltage- and calcium-sensitive fluorescent probes in human iPSC-derived cardiomyocytes;Bedut;Am. J. Physiol. Heart Circ. Physiol.,2016

3. International multisite study of human-induced pluripotent stem cell-derived cardiomyocytes for drug proarrhythmic potential assessment;Blinova;Cell Rep.,2018

4. Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias;Blinova;Toxicol. Sci.,2017

5. Deleterious effects of calcium indicators within cells; an inconvenient truth;Bootman;Cell Calcium,2018

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