Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis-Reference-Cited by-同舟云学术

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Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis

Published:2017-04 Issue:4 Volume:8 Page:856-869
ISSN:2213-6711
Container-title:Stem Cell Reports
language:en
Short-container-title:Stem Cell Reports

Author:

Bhinge Akshay,Namboori Seema C.,Zhang Xiaoyu,VanDongen Antonius M.J.,Stanton Lawrence W.

Funder

Agency for Science, Technology and Research (A∗STAR)

Publisher

Elsevier BV

Subject

Cell Biology,Developmental Biology,Genetics,Biochemistry

Reference49 articles.

1. The genetics and neuropathology of amyotrophic lateral sclerosis;Al-Chalabi;Acta. Neuropathol.,2012

2. Clinical genetics of amyotrophic lateral sclerosis: what do we really know?;Andersen;Nat. Rev. Neurol.,2011

3. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability;Bilican;Proc. Natl. Acad. Sci. USA,2012

4. Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neurons;Chen;Cell Stem Cell,2014

5. C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

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